Serveur d'exploration sur le peuplier

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Propolis allergy. (II). The sensitizing properties of 1,1-dimethylallyl caffeic acid ester.

Identifieur interne : 004D58 ( Main/Exploration ); précédent : 004D57; suivant : 004D59

Propolis allergy. (II). The sensitizing properties of 1,1-dimethylallyl caffeic acid ester.

Auteurs : B M Hausen [Allemagne] ; E. Wollenweber ; H. Senff ; B. Post

Source :

RBID : pubmed:3677659

Descripteurs français

English descriptors

Abstract

As shown in the preceding paper, propolis or bee-glue is the cause of an increasing number of allergic reactions in persons using it in external preparations and cosmetics. Propolis and its main contact allergen, 1,1-dimethylallyl caffeic acid ester, designated LB-1, show strong sensitizing properties in patients as well as in guinea pig experiments. 9 patients have been patch tested with this compound, 8 of whom reacted strongly. Chemical separation of different propolis samples and poplar bud extracts reveal that LB-1 is always present. Poplar bud secretion is the bee's major source for propolis and hence the origin of LB-1. A warning is indicated, in agreement with several other authors, that propolis should not be used in topical products because of its strong sensitizing properties.

DOI: 10.1111/j.1600-0536.1987.tb02700.x
PubMed: 3677659


Affiliations:


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Le document en format XML

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<title xml:lang="en">Propolis allergy. (II). The sensitizing properties of 1,1-dimethylallyl caffeic acid ester.</title>
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<name sortKey="Hausen, B M" sort="Hausen, B M" uniqKey="Hausen B" first="B M" last="Hausen">B M Hausen</name>
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<nlm:affiliation>Department of Dermatology, University Hospital, Hamburg, West-Germany.</nlm:affiliation>
<country xml:lang="fr" wicri:curation="lc">Allemagne</country>
<wicri:regionArea>Department of Dermatology, University Hospital, Hamburg</wicri:regionArea>
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<name sortKey="Senff, H" sort="Senff, H" uniqKey="Senff H" first="H" last="Senff">H. Senff</name>
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<name sortKey="Post, B" sort="Post, B" uniqKey="Post B" first="B" last="Post">B. Post</name>
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<term>Caffeic Acids (adverse effects)</term>
<term>Caffeic Acids (isolation & purification)</term>
<term>Cinnamates (adverse effects)</term>
<term>Dermatitis, Contact (etiology)</term>
<term>Female (MeSH)</term>
<term>Guinea Pigs (MeSH)</term>
<term>Humans (MeSH)</term>
<term>Immunization (methods)</term>
<term>Male (MeSH)</term>
<term>Middle Aged (MeSH)</term>
<term>Patch Tests (MeSH)</term>
<term>Plant Extracts (adverse effects)</term>
<term>Plants, Medicinal (MeSH)</term>
<term>Propolis (adverse effects)</term>
<term>Propolis (analysis)</term>
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<keywords scheme="KwdFr" xml:lang="fr">
<term>Acides caféiques (effets indésirables)</term>
<term>Acides caféiques (isolement et purification)</term>
<term>Adulte (MeSH)</term>
<term>Adulte d'âge moyen (MeSH)</term>
<term>Animaux (MeSH)</term>
<term>Cinnamates (effets indésirables)</term>
<term>Cochons d'Inde (MeSH)</term>
<term>Eczéma de contact (étiologie)</term>
<term>Extraits de plantes (effets indésirables)</term>
<term>Femelle (MeSH)</term>
<term>Humains (MeSH)</term>
<term>Immunisation (méthodes)</term>
<term>Mâle (MeSH)</term>
<term>Plantes médicinales (MeSH)</term>
<term>Propolis (analyse)</term>
<term>Propolis (effets indésirables)</term>
<term>Résines végétales (effets indésirables)</term>
<term>Sujet âgé (MeSH)</term>
<term>Sujet âgé de 80 ans ou plus (MeSH)</term>
<term>Tests épicutanés (MeSH)</term>
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<term>Caffeic Acids</term>
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<term>Plant Extracts</term>
<term>Propolis</term>
<term>Resins, Plant</term>
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<term>Propolis</term>
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<term>Caffeic Acids</term>
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<term>Propolis</term>
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<term>Acides caféiques</term>
<term>Cinnamates</term>
<term>Extraits de plantes</term>
<term>Propolis</term>
<term>Résines végétales</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en">
<term>Dermatitis, Contact</term>
</keywords>
<keywords scheme="MESH" qualifier="isolement et purification" xml:lang="fr">
<term>Acides caféiques</term>
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<term>Humains</term>
<term>Mâle</term>
<term>Plantes médicinales</term>
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<front>
<div type="abstract" xml:lang="en">As shown in the preceding paper, propolis or bee-glue is the cause of an increasing number of allergic reactions in persons using it in external preparations and cosmetics. Propolis and its main contact allergen, 1,1-dimethylallyl caffeic acid ester, designated LB-1, show strong sensitizing properties in patients as well as in guinea pig experiments. 9 patients have been patch tested with this compound, 8 of whom reacted strongly. Chemical separation of different propolis samples and poplar bud extracts reveal that LB-1 is always present. Poplar bud secretion is the bee's major source for propolis and hence the origin of LB-1. A warning is indicated, in agreement with several other authors, that propolis should not be used in topical products because of its strong sensitizing properties.</div>
</front>
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<AbstractText>As shown in the preceding paper, propolis or bee-glue is the cause of an increasing number of allergic reactions in persons using it in external preparations and cosmetics. Propolis and its main contact allergen, 1,1-dimethylallyl caffeic acid ester, designated LB-1, show strong sensitizing properties in patients as well as in guinea pig experiments. 9 patients have been patch tested with this compound, 8 of whom reacted strongly. Chemical separation of different propolis samples and poplar bud extracts reveal that LB-1 is always present. Poplar bud secretion is the bee's major source for propolis and hence the origin of LB-1. A warning is indicated, in agreement with several other authors, that propolis should not be used in topical products because of its strong sensitizing properties.</AbstractText>
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